中华小苦荬化学成分的研究

Chemical constituents from Ixeriduim chinese

目的研究中华小苦荬Ixeriduim chinese的化学成分。方法中华小苦荬95%乙醇提取物采用硅胶、Sephadex LH-20进行分离纯化,根据理化性质及波谱数据鉴定所得化合物的结构。结果从中分离得到13个化合物,分别鉴定为槲皮素(1)、5,7,4′-三羟基-6,8-二甲氧基黄酮(2)、木犀草素(3)、β-谷甾醇(4)、蒲公英萜醇(5)、芹菜素-7-O-β-D-葡萄糖苷(6)、β-胡萝卜苷(7)、蒲公英甾醇(8)、芹菜素(9)、豆甾醇(10)、蒲公英甾醇乙酸酯(11)、木犀草苷(12)、棕榈酸(13)。结论化合物2、5、8、11~13为首次从该植物中分离得到。

AIM To study the chemical constituents from Ixeriduim chinese(Thunb.)Tzvel..METHODS The 95% ethanol extract from I. chinese was isolated and purified by silica column and Sephadex LH-20,then the structures of obtained compounds were identified by physicochemical properties and spectral data.RESULTS Thirteen compounds were isolated and identified as quercetin(1),5,7,4′-trihydroxy-6,8-dimethoxyflavone(2),luteolin(3),β-sitosterol(4),taraxasterol(5),apigenin-7-O-β-D-glucopyranoside(6),β-daucosterol(7),pseudotaraxasterol(8),apigenin(9),stigmasterol(10),taraxasteryl acetate(11),luteoloside(12),palmitic acid(13). CONCLUSION Compounds 2,5,8,11-13 are isolated from this plant for the first time.