TORCH感染与不良妊娠及胎儿畸形关系的分析

Analysis of the relationship between TORCH infection and adverse pregnancy and fetal malformation

目的研究分析TORCH感染与不良妊娠及胎儿畸形的关系。方法 2011年10月~2018年2月我院产检孕妇243例作为研究对象,针对TORCH感染与与胎儿先天畸形的关系进行分析。结果妊娠不良孕妇其TORCH系列IgM、IgG阳性率均显著高于孕检正常者,差异具有统计学意义(P<0.05);而妊娠不良孕妇中共有32例孕妇胎儿为畸形,胎儿畸形孕妇的TORCH系列IgM、IgG阳性率与妊娠不良孕妇相较其RV、CMV病毒检出率胎儿畸形孕妇显著高于妊娠不良孕妇,差异具有统计学意义(P<0.05)。结论 TORCH系列病原体感染是导致孕妇出现不良妊娠的最主要原因,RV、CMV可能是导致胎儿畸形的因素,但因孕妇可能存在多种TORCH系列病原体感染,故而无法判定是何种病原体导致胎儿畸形,但对于RV、CMV感染孕妇需对其进行高度关注。

Objective:To study the relationship between TORCH infection and adverse pregnancy and fetal malformation. Methods:From October 2011 to February 2018,243 pregnant women in our hospital were selected as subjects to analyze the relationship between TORCH infection and congenital malformations. Results:The positive rate of TORCH series IgM and IgG in pregnant women with pregnancy was significantly higher than that in normal pregnancy(P<0.05). Among the pregnant women with poor pregnancy,32 cases were pregnant with fetal malformation,TORCH of pregnant women with fetal malformation. The positive rate of IgM and IgG in the series was significantly higher than that in pregnant women with abnormal RV and CMV virus. The difference was statistically significant(P<0.05). Conclusion:TORCH series pathogen infection is the most common cause of adverse pregnancy in pregnant women. RV and CMV may be the factors that cause fetal malformation. However,there may be multiple TORCH series pathogen infections in pregnant women,so it is impossible to determine which pathogen causes fetal malformation. However,pregnant women with RV and CMV infection need to pay close attention to it.