第一产程给予间苯三酚对产程及分娩结局的影响

Effect of application of phloroglucinol in the first stage of labor on the process of labor and delivery outcome

目的探讨第一产程中应用间苯三酚对产妇产程及分娩结局的影响。方法选取拟分娩产妇80例,随机分为观察组与对照组,各40例。于第一产程时,观察组给予间苯三酚+缩宫素诱导,对照组给予缩宫素诱导,均行常规监护处理,比较两组第一产程、第二产程、第三产程及宫颈扩张速度,分娩方式、子宫颈水肿情况、产后出血量、新生儿Apgar评分、新生儿窒息及羊水感染发生率。结果观察组的第一产程潜伏期、活跃期时间均显著短于对照组(P< 0.05),两组的第二产程、第三产程时间无显著差异(P> 0.05);观察组宫颈扩张速度快于对照组(P< 0.05),剖宫产率、宫颈水肿率、产后出血量低于对照组(P< 0.05);两组的新生儿1 min、5 min Apgar评分和新生儿窒息及羊水感染发生率比较无显著差异(P > 0.05)。结论第一产程中应用间苯三酚,可有效缩短产妇第一产程时间,减少产后出血量,降低剖宫产率。

Objective To explore the effect of application of phloroglucinol in the first stage of labor on the process of labor and delivery outcome. Methods A total of 80 puerperae waiting for delivery were selected and randomly divided into observation group and control group, with 40 cases each. At the first stage of labor, phlorogucinol combined with oxytocin was performed on the observation group for induction of labor, and oxytocin was performed on the control group for induction of labor. Both groups received routine monitoring. The first stage of labor, the second stage of labor, the third stage of labor along with the rate of cervical dilatation,delivery mode, cervical edema, volume of postpartum hemorrhage, neonatal Apgar score, incidence of neonatal asphyxia, and incidence of amniotic fluid infection were compared between the two groups. Results The course of latency and active period in the first stage of labor in the observation group were significantly shorter than those in the control group(P < 0.05), and there were no significant differences in the course of the second stage of labor and the third stage of labor between the two groups(P > 0.05). The rate of cervical dilatation in the observation group was higher than that in the control group(P < 0.05), and the cesarean section rate,cervical edema rate and volume of postpartum hemorrhage were lower than those in the control group(P < 0.05). There were no significant differences in the neonatal Apgar score at one and five minutes after birth, incidence of neonatal asphyxia and incidence of amniotic fluid infection between the two groups(P > 0.05). Conclusion Application of phloroglucinol in the first stage of labor can effectively shorten the course of the first stage of labor, reduce the volume of postpartum hemorrhage and decrease the cesarean section rate.