摘要
It was early 1990 that we had gathered at Arnie Levine's home for dinner to celebrate the transition of several postdoctoral fellows to faculty positions in academia.As a new postdoctoral fellow in his lab,I was thrilled to have the opportunity to spend some personal time with Arnie.We were discussing the paradigm shift made by his group a year earlier that p53 is a tumour suppressor (Finlay et at.,1989) and not an on cogene,as origi nally thought for a decade after its original discovery (Lane and Crawford,1979;Linzer and Levine,1979).
