摘要
目的探讨多系统萎缩(multiple system atrophy,MSA)的临床表现和影像学特点,避免误诊.方法报告2例MSA并进行分析.结果 1例62岁女性,病程4 a,表现为尿失禁、便秘、行走不稳,头颅MRI:脑桥中央竖线样信号增高并壳核外侧线样高信号.另1例53岁女性,病程3 a,表现为双下肢乏力、言语含糊、行走不稳,头颅M RI:脑桥见"十字征".结论最初的症状中出现体位性低血压,并且MRI出现"十字征"和"壳核边缘高信号征"有助于MSA的准确诊断.
Objective To investigate the clinical and imaging features of multiple system atrophy (MSA)and to avoid misdiagnosis. Methods Two cases of MSA were reported and analyzed. Results A 62-year-old female with a course of 4 years showed incontinentia urinae,constipation and walking instability.Cranial MRI showed enhancement of linear signals in the central pontine and linear T2-high intensity signals around the lateral putamen.Another 53-year-old woman,with a 3-year course of disease,presented with weakness of the lower extremities,vague speech and unstable walking.Cranial MRI showed the presence of "hot cross bun" sign in the pontine. Conclusion Postural hypotension appears in the initial symptoms,and "hot cross bun" sign and "hyperintense putamen rim" sign in MRI are helpful for the accurate diagnosis of MSA.
作者
张捷
张林艳
许多
王志坚
江文婷
ZHANG Jie;ZHANG Linyan;XU Duo;WANG Zhijian;JIANG Wenting(Department of Neurology,Fuzhou Neuropsychiatric Hospital,Fuzhou 350008,China)
出处
《中国实用神经疾病杂志》
2019年第13期1501-1504,共4页
Chinese Journal of Practical Nervous Diseases
关键词
多系统萎缩
体位性低血压
十字征
低血压
影像学特点
Multiple system atrophy
Postural hypotension
"Hot cross bun" sign
Hypotension
Imaging features
