毒性分级为“有毒”的药材范围及相关问题探讨

Discussions on the range of toxic Chinese herbal medicines and other correlated issues

本文对我国法定药材标准中毒性分级为“有毒”的药材范围进行了整理。结果显示,此类有毒药材共有150种。建议加强毒性药材的管理,提高临床用药的安全性;加强有毒药材所含毒性成分的基础研究;在相应药材的法定标准中建立毒性成分的质控项目;对处方含有毒药材的中药新药加强针对性研究,保证用药安全。

The range of toxic Chinese herbal medicines was summarized according to the legal Chinese medicinal materials specifications. The result showed that there are 150 kinds of toxic Chinese herbal medicine. Some suggestions were put forward as follows: the management of toxic Chinese herbal medicine should be strengthened to improve the safety of their clinical use;more basic research on the toxic components need to be carried out;the quality control methods of toxic components should be established in their legal standards;specific toxicity research on new drugs which contain toxic Chinese herbal medicine are warranted to make sure they are safely used in clinical practice.