摘要
2015年3月至2018年2月,在合肥市招募孕13~27周、年龄为18~45岁的常住单胎妊娠孕妇4 728名,分析维生素D状态的变化趋势.2015—2017年的血清25(OH)D水平分别为(43.2± 18.4)、(39.3±15.1)和(36.6±17.0)nmol/L,维生素D缺乏率分别为69.5%、77.6%和81.4%.与2015年相比,2016年和2017年孕妇的血清25(OH)D水平分别下降5.23(95 %CI :4.10~6.35)和7.98(95%CI :6.77~9.19)nmol/L;2016年和2017年孕妇维生素D缺乏风险的OR(95%CI)值分别为1.88(1.57~2.24)、2.41(1.98~2.93).
From March 2015 to February 2018, 4 728 women aged 18 to 45 years old with single-pregnancy at the gestational age of 13 to 27 weeks in Hefei were recruited to analyze the trend of vitamin D status. The average levels of serum 25(OH)D in 2015, 2016 and 2017 were (43.22±18.41) nmol/L,(39.3±15.1) nmol/L and (36.6±17.0) nmol/L, and the prevalence of vitamin D deficiency were 69.5%, 77.6% and 81.4%, respectively. Compared with 2015, the levels of serum 25(OH)D in pregnant women in 2016 and 2017 decreased by 5.23 (95%CI: 4.10-6.35) nmol/L and 7.98 (95%CI: 6.77-9.19) nmol/L. The OR (95%CI) values for the risk of vitamin D deficiency were 1.88 (95%CI : 1.57-2.24) and 2.41 (95%CI : 1.98-2.93).
作者
尹万军
陶瑞雪
张英
蒋晓敏
金丹
姚梦楠
余宛琪
朱鹏
Yin Wanjun;Tao Ruixue;Zhang Ying;Jiang Xiaomin;Jin Dan;Yao Mengnan;Yu Wanqi;Zhu Peng(Department of Matemaly Child&Adolescent Healthy School of Public Healthy Anhui Medical University,Hefei 230032,China;Department of Obstetrics and Gynecology,the First Peopled Hospital of Hefei City,Hefei 230001,China;Department of Obstetrics and Gynecology,the First Affiliated Hospital of Anhui Medical University,Hefei 230022,China;Department of Obstetrics and Gynecology,Anhui Women and Child Health Care Hospital,Hefei 230001,China;Anhui Provincial Key Laboratory of Population Health and Aristogenics,Hefei 230032,China)
出处
《中华预防医学杂志》
CAS
CSCD
北大核心
2019年第9期947-950,共4页
Chinese Journal of Preventive Medicine
基金
国家自然科学基金(81872631、81472991)
安徽省高校优秀青年人才基金(gxyqZD2018025)
国家级大学生创新训练项目(201710366029).
关键词
孕妇
维生素D
维生素D缺乏
Pregnant women
Vitamin D
Vitamin D deficiency
