摘要
通过Suzuki偶联反应构建碳-碳键是有机合成的一种重要策略。近年来,酚类结构通过构建磺酸酯,增强底物的离去活性而进行Suzuki偶联反应,扩大了底物的适应性,引起化学家们的广泛关注。该方法底物来源广泛、制备方法简单,为碳-碳键的构建提供了一种绿色、高效的途径,具有广泛的应用前景。本文按不同过渡金属形成的催化剂种类,对近年来对甲苯磺酸酯、甲磺酸酯、取代胺基磺酸酯等与芳基硼酸的Suzuki偶联反应的研究进展进行了综述。
The formation of carbon-carbon bonds by Suzuki Cross-coupling reaction is a powerful strategy for organic synthesis. In recent years, the Suzuki Cross-coupling reactions of phenolic derivatives by formation of aryl sulfonates have attracted much research interest from chemists, due to enhancing the substrates’ leaving activity and expanding the adaptability of the substrates. The present protocol, with a wide range of substrates and easy preparation, provides a green and efficient approach to construct carbon-carbon bonds, which has widely prospect in application. This review summarized the recent progress in the Suzuki Cross-coupling reaction of tosylates, mesylates and substituted amino sulfonates with arylboronic acid on the basis of different types of catalysts formed by different transition metals.
作者
王婷
代祯
黄冲
黄晴菲
朱槿
王启卫
WANG Ting;DAI Zhen;HUANG Chong;HUANG Qing-fei;ZHU Jin;WANG Qi-wei(Sichuan Polytechnic Technician College, Chengdu 611130, China;Chengdu Institute of Organic Chemistry,Chinese Academy of Sciences, Chengdu 610041, China;University of Chinese Academy of Science, Beijing 100049, China)
出处
《合成化学》
CAS
北大核心
2019年第9期763-770,共8页
Chinese Journal of Synthetic Chemistry
基金
中国科学院“西部之光”人才培养计划