血小板衍生生长因子对面部凹陷自体脂肪移植成活率的影响

Effect of Platelet-derived Growth Factor on the Survival Rate of Facial Fat Autograft

目的:探讨血小板衍生生长因子(PDGF)对面部凹陷自体脂肪移植成活率的影响。方法:选取我院自2016年3月-2017年11月收治的62例面部凹陷患者,根据治疗方案的不同分为观察组和对照组,对照组30例患者仅采用自体脂肪颗粒移植治疗,观察组32例患者在对照组基础上加用血小板衍生生长因子治疗,比较两组患者治疗的优良率和并发症的发生情况。结果:治疗后,观察组患者的优良率为93.75%,明显高于对照组(73.33%,P<0.05)。观察组患者治疗后3个月、6个月时身体脂肪吸收率明显高于术后1个月时(P<0.05),且与对照组同时点比较,观察组患者治疗后3个月、6个月时的身体脂肪吸收率显著升高(P<0.05)。观察组患者对治疗满意度为87.55%,显著高于对照组(70.0%,P>0.05)。结论:血小板衍生生长因子应用于治疗面部凹陷能够有效提高自体脂肪移植的成活率。

Objective: To investigate the effect of platelet-derived growth factor(PDGF) on the survival rate of facial fat autograft.Methods: 62 cases of patients with facial depression treated in our hospital from March 2015 to July 2017 were selected as the experimental subjects and divided into two groups according to the different treatment schemes. 30 cases in the control group were treated with autologous fat granule transplantation only, and 32 cases in the observation group were treated with small plate derived growth factor on the basis of control group, the excellent and good rate of treatment and incidence of complications were compared between the two groups. Results: After treatment, the excellent and good rate of patients in the observation group was 93.75%, it was significantly higher than that of the control group(73.33%, P<0.05). The body fat absorption rate in the observation group was significantly higher than those at 3 months and 6 months after treatment(P<0.05), which were higher than those of the control group at 3 months and 6 months after treatment(P<0.05);the satisfaction rate of observation group was 87.55%, it was obviously higher than that of the control group(70%,P<0.05). Conclusion: Platelet-derived growth factor can improve the survival rate of autologous fat transplantation in the treatment of facial depression.