响应面分析法优化聚丙烯酰胺微球大小工艺

Synthesis of Specific Particle Size PMA Particles by Response Surface Methodology

聚丙烯酰胺类物质具有超强的吸水性,本文利用Design-Expert软件中的响应面分析法来合成粒径150nm的PAM微粒,模拟结果如下:反应温度70.54℃,反应时间60.33min,引发剂用量0.46%.通过验证实验可得在该条件下合成的PAM微粒平均粒径在150nm,说明此分析方法可以通过计算自由控制各因素条件来控制合成特定粒径的PAM微粒.

Polyacrylamide has super water absorption.In this paper,response surface analysis method in Design-Expert software is used to synthesize PAM particles with particle size of 150 nm.The simulation results are as follows: reaction temperature 70.54 "C,reaction time 60.33 min, initiator dosage 0.46%.The average particle size of PAM particles synthesized under this condition is 150 nm,which indicates that this method can control the synthesis ofPAMparticles with specific particle size by calculating the free control of various factors.