含柴胡中成药的质量控制方法探讨

Discussion on Quality Control Methods for Chinese Patent Medicines Containing Bupleurum

柴胡药材使用品种混乱,基原不清,常有掺伪正品柴胡、非药用部位混用等质量问题,故造成含柴胡中成药质量良莠不齐,亟需建立针对性的质量控制方法。笔者基于柴胡及其中成药现行标准的质量控制方法,结合小柴胡颗粒品种实例,对柴胡及其中成药的标准提高和补充检验方法进行探讨,为含柴胡中成药的质量控制、质量监督和规范生产提供参考,促进其内在质量的提升。

There are many problems in the use of Bupleurum medicinal materials such as confusion in variety,unclearness in origin and quality problems,e. g.,adulteration of authentic Bupleurum and mixing of non-medicinal parts. Therefore,the quality of Chinese patent medicines containing Bupleurum chinense is variable,and it is necessary to establish targeted quality control methods. Based on the quality control methods of Bupleurum and its Chinese patent medicines,combined with the example of Xiaochaihu granules,this paper discussed the quality standard improvement and supplementary test methods of Bupleurum and its Chinese patent medicines,aiming to provide reference for the quality control,quality supervision and standardized production of Chinese patent medicines containing Bupleurum and promote the improvement of its intrinsic quality.