胺碘酮在急诊冠心病快速心律失常患者治疗中的运用分析

Analysis of the Use of Amiodarone in the Treatment of Patients with Acute Arrhythmia in Emergency Coronary Heart Disease

目的分析对于急诊冠心病快速心律失常患者使用胺碘酮进行治疗的治疗效果,为临床提供参考。方法方便选择在该院2016年3月-2017年3月接受治疗的急诊冠心病快速心律失常患者(120例)为研究对象并随机将这些患者分为观察组(60例)和对照组(60例)。对于两组患者均实施常规的药物治疗措施,然后对照组患者在此基础上实施辛伐他汀胶囊以及依泽替米贝进行治疗;观察组患者实施的治疗措施是在常规药物治疗的基础上使用静脉滴注胺碘酮进行治疗。治疗结束后对比两组患者临床治疗有效率、心功能指标及血脂指标。结果观察组患者治疗总有效率为98.4%,显著高于对照组80.00%,差异有统计学意义(χ^2=7.203,P=0.007);观察组患者LVESD、LVEDD、LVEF分别为(35.45±9.34)mm、(52.45±5.56)mm、(47.23±6.26)%,均显著优于对照组,差异有统计学意义(t=12.896、14.562、12.689,P<0.05);观察组患者HDL-C、TC、TG、LDL-C分别为(2.89±1.26)mmol/L、(4.02±1.46)mmol/L、(3.35±1.98)mmol/L、(2.65±1.25)mmol/L,均显著优于对照组,差异有统计学意义(t=15.067、16.526、13.996、15.784,P<0.05)。结论对于急诊冠心病快速心律失常患者使用胺碘酮进行治疗具有较好的治疗效果,值得推广。

Objective To analyze the therapeutic effect of amiodarone in patients with acute arrhythmia in emergency coronary heart disease,and provide reference for clinical application.Methods Patients with acute coronary heart disease tachyarrhythmia (120 cases) who were treated in our hospital from March 2016 to March 2017 were conveniently selected in the study and randomly divided into observation group (60 cases) and control group (60 cases).Conventional drug treatment was performed in both groups,and then the control group was treated with simvastatin capsules and ezetimibe.The treatments in the observation group were based on conventional drug therapy.Intravenous infusion of amiodarone for treatment.After treatment,the clinical treatment efficiency,cardiac function index and blood lipid index were compared between the two groups.Results The total effective rate of the observation group was 98.4%,which was significantly higher than that of the control group (80.00%).The difference was statistically significant(χ^2=7.203,P=0.007);LVESD,LVEDD,LVEF in the observation group (35.45±9.34)mm,(52.45±5.56)mm,and (47.23±6.26)%,respectively,were significantly better than the control group,the difference was statistically significant(t=12.896,14.562,12.689,P<0.05);HDL-C in the observation group,TC,TG,and LDL-C were (2.89±1.26)mmol/L,(4.02±1.46)mmol/L,(3.35±1.98)mmol/L,and (2.65±1.25)mmol/L,respectively,which were significantly better than the control group,and the difference was statistically significant.(t=15.067,16.526,13.996,15.784,P<0.05).Conclusion The use of amiodarone in patients with acute coronary heart disease and tachyarrhythmia has a good therapeutic effect and is worthy of promotion.