T2WI直方图对椎体压缩性骨折进展中骨髓水肿及疼痛变化的评价

Evaluation of T2WI histogram to bone marrow edema and pain changes in the development of vertebral compression fractures

目的:探讨T2WI直方图在椎体压缩性骨折时间判定及疼痛评价中应用的可行性。方法:将32例因骨质疏松所致胸腰椎压缩性骨折的患者纳入研究,在骨折30、90d时行常规MRI检查和疼痛评分。对以上时间的T2WI压脂图像进行直方图分析,计算直方图的平均值、中位数、标准差、峰度值和偏度值,比较30d和90d时各参数之间的差异,并探讨各参数与疼痛评分之间的相关性。结果:骨折90d时,T2WI直方图的平均值、中位数、标准差及偏度值均低于30d时(均P<0.05),平均值、中位数与疼痛评分有显著相关性,相关系数分别为0.892、0.912。结论:T2WI直方图参数中平均值和中位数能帮助判断骨折时间,同时与疼痛程度有一定相关性,可为临床诊疗方案的制订提供一定依据。

Objective:To explore the feasibility of the T2WI histogram in analysis the time of vertebral compression fractures and pain evaluation. Methods:Thirty-two patients with thoracolumbar vertebral compression fractures due to osteoporosis were enrolled in the study. Conventional magnetic resonance imaging and pain scores were obtained in the 30th and 90th day after fracture. Histogram analysis was performed on FS-T2WI of different days after fracture. The mean,median,standard deviation,kurtosis and skewness of histogram were calculated. The differences between parameters at the 30th day and the 90th day were compared,and the correlation between parameters and pain score was calculated. Results:At the 90th day of fracture,the mean,median,standard deviation and skewness of T2WI histogram were lower than those at the 30th day,with significant statistical difference (P<0.05). Mean,median and pain scores were significantly correlated,with correlation coefficients of 0.892 and 0.912,respectively. Conclusions:The parameters of T2WI histogram can help to differentiate fresh and old fractures,and have a certain correlation with the degree of pain,which provides certain evidence for the clinical diagnosis and treatment.