期刊文献+

孟鲁司特钠在老年哮喘—慢性阻塞性肺疾病重叠综合征中的应用价值 被引量:2

下载PDF
导出
摘要 目的:探讨孟鲁司特钠在老年哮喘—慢性阻塞性肺疾病重叠综合征(ACOS)中的应用价值。方法:将100例ACOS患者随机分为对照组(n=50)和治疗组(n=50)。对照组给予常规治疗,治疗组在此基础上加用孟鲁司特钠。比较两组肺功能(FEV1、FEV1/FVC)、哮喘症状评分(ACT评分)、慢阻肺症状评分(CAT评分)、不良反应发生率和1年内ACOS复发率。结果:治疗后,两组患者FEV1、FEV1/FVC和ACT评分均上调(P<0.05),CAT评分均下调(P<0.05);治疗组FEV1、FEV1/FVC和ACT评分明显高于对照组(P<0.05),CAT评分明显低于对照组(P<0.05);治疗组不良反应发生率和1年内ACOS复发率均明显低于对照组(P<0.05)。结论:应用孟鲁司特钠可显著改善老年ACOS患者肺功能,缓解临床症状,减少不良反应和复发风险。
作者 金虹
出处 《医学理论与实践》 2019年第17期2739-2740,共2页 The Journal of Medical Theory and Practice
  • 相关文献

参考文献6

二级参考文献43

  • 1Global Strategy for the Diagnosis, Management and Prevention of COPD[R]. Global Initiative for Chronic Obstructive Lung Disease (GOLD), 2015. Available from: http://www.goldcopd.org/.
  • 2Global Strategy for Asthma Management and Prevention[R]. Global Initiative for Asthma (GINA), 2014. Available from: http://www.ginasthma.org/.
  • 3Barrecheguren M, Miravitlles M. Asthma-COPD overlap syndrome from a COPD perspective[J]. Europ Respir News, 2013, XXI(82): 100-107.
  • 4Louie S, Zeki A A, Schivo M, et al. The asthma-chronic obstructive pulmonary disease overlap syndrome: pharmacotherapeutic considerations[J]. Expert Rev Clin Pharmacol, 2013, 6(2): 197-219.
  • 5Zeki A A, Schivo M, Chan A, et al. The Asthma-COPD Overlap Syndrome: A Common Clinical Problem in the Elderly[J]. J Allergy (Cairo), 2011, 2011:861926.
  • 6Shaya F T, Dongyi D, Akazawa M O, et al. Burden of concomitant asthma and COPD in a Medicaid population[J]. Chest, 2008, 134(1):14-19.
  • 7Gibson P G, Simpson J L. The overlap syndrome of asthma and COPD: what are its features and how important is it? [J]. Thorax, 2009, 64(8):728-735.
  • 8DiSantostefano R L, Li H, Rubin D B, et al. Which patients with chronic obstructive pulmonary disease benefit from the addition of an inhaled corticosteroid to their bronchodilator? A cluster analysis[J]. BMJ Open, 2013, 3(4): e001838.
  • 9Hardin M, Silverman E K, Barr R G, et al. The clinical features of the overlap between COPD and asthma[J]. Respir Res, 2011, 12:127.
  • 10李善群,钮善福,聂莉,陈琪,张志风,张倩,总结.哮喘症状评分及PEF评价普鲁司特治疗支气管哮喘的临床疗效[J].中国临床医学,2008,15(3):318-321. 被引量:38

共引文献259

同被引文献14

二级引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部