急性混合型分水岭脑梗死中医证候与狭窄血管支数、狭窄程度及预后的相关性研究

Correlation between TCM syndrome and number of artery stenosis, stenosis degree and prognosis in acute mixed watershed cerebral infarction

目的:观察急性混合型分水岭脑梗死(Mixed Cerebral Watershed Infarction,MCWI)中医证候与狭窄血管支数、狭窄程度、预后的相关性。方法:对纳入的170例患者按证候分组,记录狭窄血管支数、狭窄程度,入院1d、7d美国国立卫生研究所卒中量表(National Institute of Health Stroke Scale,NIHSS)评分,入院1月后随访Barthel评分(Barthel Index,BI),运用SPSS16.0进行统计分析。结果:不同中医证候内部血管狭窄程度及预后构成不同(P<0.05),以气虚血瘀组为对照组,各比较项目秩均值(或构成比)均高于余证候组(P<0.017);尚不能认为不同证候血管狭窄支数构成不同(P>0.05)。结论:急性MCWI气虚血瘀证血管狭窄程度更重,临床转归易于恶化,近期预后不良。

Objective To observe the correlation between TCM syndromes of MCWI and the number of artery stenosis, stenosis degree and prognosis. Methods The 170 patients were grouped according to syndrome. Number and degree of stenosis, NIHSS scores on admission 1d and 7d and BI score on follow-up after admission 1 month were recorded.All the date are analyzed by SPSS 16.0. Results In TCM syndromes, the composition of the number of artery stenosis and the prognosis were different (P<0.05).With Qi deficiency and blood stasis group as the control group, the rank mean (or constituent ratio) of each comparison item was higher than that of the other syndrome groups (P<0.017);it was not considered that the number of vascular stenosis branches in the syndrome was different (P>0.05).Conclusion Acute MCWI with Qi deficiency and blood stasis syndrome has more severe stenosis, prone to deterioration of clinical prognosis and poor prognosis in short-term.