安柯微创旋切手术治疗良性乳腺肿物的效果及对患者血清炎性因子水平的影响

Effect of minimally invasive rotary resection on benign breast masses and its effect on serum inflammatory factors in patients

目的 探讨安柯微创旋切手术治疗良性乳腺肿物的临床效果及对患者血清炎性因子水平的影响。方法 选择2017年8月至2018年9月治疗的良性乳腺肿物患者90例作为对象,随机数字表分为两组,各45例。对照组给予常规手术治疗,观察组采用安柯微创旋切手术治疗,治疗后对患者效果进行评估,比较两组手术情况,炎性因子CRP、TNF-α及IL-6水平变化和两组患者术后并发症发生情况。结果 观察组手术时间、术中出血量、切口长度分别为(26.24±4.81)min、(12.58±3.44)ml、(2.68±0.20)mm,均低于对照组,差异均有统计学意义(均P<0.05);治疗前,两组患者CRP、TNF-α、IL-6水平比较,差异均无统计学意义(均P>0.05);治疗后,观察组CRP、TNF-α、IL-6水平分别为(9.7±3.7)mg/L、(13.6±4.1)μg/L、(9.8±4.5)ng/L,均低于对照组,差异均有统计学意义(均P<0.05);两组患者经治疗后6个月随访,均未发现病灶复发;观察组并发症发生率为8.9%(4/45),明显低于对照组24.4%(11/45),差异有统计学意义(P<0.05)。结论 将安柯微创旋切手术用于良性乳腺肿物患者中有助于提高临床疗效,能降低炎症因子水平,减少并发症的发生,值得推广应用。

Objective To investigate the clinical effect of Anke minimally invasive rotary resection on benign breast tumors and its influence on serum inflammatory factors. Methods Ninety patients with benign breast tumors treated from August 2017 to September 2018 were selected as subjects and were randomly divided into control group (n=45) and observation group (n=45). The control group was treated with routine surgery, while the observation group was treated with Anke minimally invasive rotary resection. After treatment, the effect of patients was evaluated. The operation conditions, changes of levels of inflammatory factors (CRP, TNF-alpha, and IL-6), and the occurrence of postoperative complications were compared between the two groups. Results The operation time, the amount of bleeding during operation, and incision length of the observation group [(26.24±4.81) min,(12.58±3.44)ml,(2.68±0.20)mm] were significantly less than those of the control group (P<0.05). The levels of CRP, TNF-alpha, and IL-6 in the two groups were not significantly different before treatment (P>0.05). After treatment, the levels of CRP, TNF-alpha, and IL-6 in the observation group [(9.7±3.7)mg/L,(13.6±4.1)μg/ L,(9.8±4.5)ng/L] were significantly lower than those in the control group (P<0.05). After 6 months of follow-up, no recurrence was found in both two groups. The incidence of complications in the observation group was 8.9%(4/45), which was significantly lower than that in the control group [24.4%(11/45)](P<0.05). Conclusion Anke minimally invasive rotary excision is helpful to improve the clinical efficacy, reduce the level of inflammatory factors and complications in patients with benign breast tumors, which is worthy of popularization and application.