羌活胜湿汤加味治疗腰椎间盘突出症急性期的疗效研究

Effects of Modified Qianghuo Shengshi Decoction on Patients with Lumbar Disc Herniation in Acute Stage

目的观察羌活胜湿汤加味治疗腰椎间盘突出症急性期的临床疗效及其作用机制。方法124例患者随机分为对照组和治疗组各62例。对照组给予常规治疗,治疗组在对照组常规治疗的基础上加用羌活胜湿汤加味治疗,治疗21d。分析比较两组的临床疗效,治疗前、治疗14、21d后的中医证候积分、疼痛视觉模拟评分法评分(VAS)、日本骨科协会下腰痛功能评价表评分(JOA)、Oswestry功能障碍指数(ODI)、腓总神经传导速度、胫神经传导速度。结果治疗21d后,治疗组总有效率96.77%高于对照组的85.48%(P<0.05)。治疗前,两组中医证候积分比较,差异无统计学意义(P>0.05)。治疗后14、21d,两组中医证候积分均较治疗前降低,且治疗组各时间点降低程度优于对照组(均P<0.05)。治疗前,两组VAS、JOA、ODI评分比较,均差异不明显(均P>0.05)。治疗后14、21d,两组VAS、ODI评分均较治疗前降低,且治疗组各时间点降低程度优于对照组;两组JOS评分均较治疗前升高,且各时间点治疗组升高程度优于对照组(均P<0.05)。治疗前,两组腓总神经传导速度和胫神经传导速度比较,差异均无统计学意义(均P>0.05);治疗后14、21d,两组腓总神经传导速度和胫神经传导速度均较治疗前提高,且各时间点治疗组提高程度均优于对照组(均P<0.05)。结论羌活胜湿汤加味治疗腰椎间盘突出症急性期可以提高疗效、缓解疼痛、改善神经传导速度和腰椎功能。

Objective:To study the effects of Modified Qianghuo Shengshi Decoction in the treatment of patients with Lumbar Disc Herniation(LDH)in acute Stage.Methods:124 patients were randomly divided into the control group and the treatment group,62 cases in each.The control group received routine treatment,while the treatment group were treated with Modified Qianghuo Shengshi Decoction additionally for 21 days.The clinical efficacy of the two groups was analyzed.TCM syndrome scores,VAS,JOA,ODI,CPNMCV and NTMCV were measured before treatment and 14 d and 21 d after treatment.Results:The total effective rate of the treatment group was significantly higher than that of the control group(P < 0.05).After 14 days and 21 days,TCM syndrome score,VAS score and ODI score of the two groups were lower than before treatment,but the treatment group reduced significantly(P < 0.05);JOA score,CPNMCV and NTMCV increased in the two groups,but the treatment group increased significantly(P < 0.05).Conclusion:Modified Qianghuo Shengshi Decoction could improve the curative effect,relieve pain,improve nerve conduction velocity and lumbar function.