L-乳酸丙酯的合成工艺优化

Optimization of synthesis process of propyl L-lactate

对乳酸丙酯的合成工艺条件如醇酸比、催化剂用量、反应时间进行了优化。实验采用间歇式反应精馏方法提高转化率。结果表明醇酸物质的量比为3∶1时转化率最高,催化剂用量为2%时转化率达到73%,反应时间为6h时最优。

In this paper,the conditions were optimized,including the ratio of propyl alcohol and L-lactic acid,catalyst dosage and reaction time.The batch reaction distillation method was used to improve the percent conversion.The results show that the highest conversion is 73%when the ratio of propyl alcohol and L-lactic acid is 3∶1,he catalyst dosage is 2%,and the optimal reaction time is 6 hours.