生物医用材料用于药物递送系统的研究进展

Research progress of biomedical materials for drug delivery systems

生物医用绿色载体材料因其独特的结构和优异的性能,被广泛应用于医药、医疗和食品等领域,并发挥着越来越多的作用。特别是生物医用载体材料用于药物递送系统,可用载体材料将抗癌药物包裹在内,靶向、缓释和控释递送药物至肿瘤部位,有效治疗癌症,并且避免对人体正常组织的毒副作用,生物医用材料载药微球已是当前的研究热点之一。主要论述了天然以及合成的生物医用载体材料,对目前新型医用载体的制备以及应用进行了介绍,并对目前抗癌药物载体存在的问题进行的归纳总结,对其研究方向也进行了展望。

Due to its unique structure and excellent properties, biomedical green carrier materials are widely used in the fields of medicine, medicine treatment, food and so on, and play an increasingly important role. Especially, biomedical carrier material for drug delivery system can encapsulate anticancer drugs in it, which deliver anticancer drugs with target, slow-release and controlled-release to tumor sites, effectively treat cancer, and avoid toxic and side effects on normal human tissues. Biomedical green carrier materials have become one of the current research hotspots. The natural and synthetic biomedical carrier materials were mainly introduced. The preparation and application of the new medical carrier at present were reviewed. The problems existing in the current anti-cancer drug carrier were briefly summarized. The research direction in recent years was prospected.