经尿道等离子前列腺电切术联合睾丸切除术对中晚期前列腺癌病情恢复的影响

Effect of transurethral plasma prostatectomy combined with orchiectomy on the recovery of advanced prostate cancer

目的研究经尿道等离子前列腺电切术联合睾丸切除术对中晚期前列腺癌病情恢复的影响。方法选取我院2014年8月至2018年5月收治的50例中晚期前列腺癌患者为研究对象,采用随机数字表法将其分为对照组和观察组,每组25例。对照组行常规前列腺和睾丸联合切除术,观察组行经尿道等离子前列腺电切术联合睾丸切除术。比较两组治疗效果。结果两组患者的手术时间无明显差异(P>0.05),观察组的术中出血量少于对照组,住院时间、置管时间均短于对照组,差异具有统计学意义(P<0.05)。手术后,观察组的IPSS评分、残余尿量、前列腺体积、血清PSA水平均低于对照组,MFR高于对照组,差异具有统计学意义(P<0.05)。观察组的躯体功能、角色功能、情绪功能、认知功能、社会功能及总体健康评分均高于对照组(P<0.05)。结论经尿道等离子前列腺电切术联合睾丸切除术治疗中晚期前列腺癌患者效果显著,能促进患者病情恢复,提高患者生活质量,值得临床推广。

Objective To study the effects of transurethral plasma prostatectomy combined with orchiectomy on the recovery of advanced prostate cancer. Methods A total of 50 patients with advanced prostate cancer admitted in our hospital from August 2014 to May 2018 were selected as the research objects. They were divided into control group and observation group by random number table method, with 25 cases in each group. The control group underwent conventional combined prostatectomy and orchiectomy, while the observation group underwent transurethral plasma prostatectomy combined with orchiectomy. The therapeutic effects between the two groups were compared. Results There was no significant difference in operation time between the two groups(P>0.05), the amount of bleeding during operation in the observation group was less than that in the control group, and the hospitalization time and catheterization time in the observation group were shorter than those in the control group, the difference were statistically significant(P<0.05).After operation, the IPSS score, residual urine volume, prostate volume and serum PSA level of the observation group were lower than those of the control group, and the MFR was higher than that of the control group, the differences were statistically significant(P <0.05). The scores of physical function, role function, emotional function, cognitive function,social function and general health in the observation group were higher than those in the control group(P <0.05).Conclusion Transurethral plasma prostatectomy combined with orchiectomy in the treatment of advanced prostate cancer patients has a significant effect, which can promote the recovery of patients and the quality of life. It is worthy of clinical promotion.