慢性肾脏病与肥胖相关性的研究进展

Advances in research on the relationship between chronic kidney disease and obesity

肥胖已成为一种全球性的流行病,其对糖尿病、心血管疾病和慢性肾脏病(CKD)的风险均有影响。肥胖本身可导致肾脏病变,称为肥胖相关性肾病(ORG);肥胖是慢性肾脏病的危险因素,但在透析患者肥胖却显示"逆流行病学现象";同时肥胖也是移植肾失功及患者死亡的独立危险因素。2017年世界肾脏日主题是关于肥胖与慢性肾脏病的关系,口号是"健康的肾脏需要健康的生活方式"。

Obesity has become a global epidemic that affects the risk of diabetes,cardiovascular disease,and chronic kidney disease( CKD). Obesity itself can cause damage to the kidney,called obesityrelated glomerulopathy( ORG). Obesity is a risk factor for CKD,but shows the "reversed-epidemiology phenomenon"in dialysis patients. Besides,obesity is an independent risk factor of both the graft failure and the patient death. The theme of World Kidney Day in 2017 was on the relationship between obesity and CKD,with a slogan of" advocating healthy lifestyle for healthy kidneys".