摘要
健康人呼气中即含有一氧化氮。生理状态下,鼻呼气一氧化氮主要由鼻窦产生,少量产生于鼻腔黏膜,口呼气一氧化氮主要来自于肺泡和支气管,当气道发生疾病时,则可影响呼出气一氧化氮的浓度。近年来随着科技水平的不断提高,鼻呼气一氧化氮的测定在儿童上气道疾病中得到广泛应用,其具有定量、无创、简单、安全等特点。现就鼻呼气一氧化氮的测定方法及其在儿童鼻炎、鼻窦炎、鼻息肉、腺样体肥大等上气道疾病的临床应用方面进行阐述。
The exhaled air of healthy people contains nitric oxide.Under the physiological condition, nasal nitric oxide(NNO) comes primarily from the sinuses, a little is produced in the nasal mucosa.Fractional exhaled nitric oxide is mainly from the trachea and bronchus.When airway diseases occur, it can influence the concentration of exhaled nitric oxide.Therefore, with the continuous improvement of technology in recent years, the measurement of NNO has been widely used in upper airway diseases of children.It is characteristics of quantitative, non-invasive, simple and safe.This article reviews the measurement methods of NNO and its clinical application in children upper airway diseases such as rhinitis, sinusitis, nasal polyps and adenoid hypertrophy.
作者
鲍燕敏
卢清华
Bao Yanmin;Lu Qinghua(Department of Respiration,Shenzhen Children’s Hospital, Shenzhen 518000, Guangdong Province,China)
出处
《中华实用儿科临床杂志》
CSCD
北大核心
2019年第16期1207-1210,共4页
Chinese Journal of Applied Clinical Pediatrics
基金
广东省医学科研基金(A2017213).
