牙周牙髓联合病变应用不同消毒药物行根管治疗的效果观察

Effects of root canal therapy with different disinfectant drugs in patients with periodontal pulp combined disease

目的探讨牙周牙髓联合病变患者应用不同消毒药物行根管治疗的临床效果.方法选取2017年6月至2018年6月于西山煤电(集团)职工总医院接受根管治疗的牙周牙髓联合病变患者120例,以随机数字表法分为观察组和对照组,每组60例.观察组给予替硝唑溶液配合盐酸米诺环素治疗,对照组给予次氯酸钠溶液配合氢氧化钙、洗必泰治疗.比较两组治疗效果,分析治疗前后两组患者牙周相关指标变化.结果治疗12周,观察组总有效率(98.33%,59/60)高于对照组(90.00%,54/60).治疗前,两组患者临床附着水平(CAL)、菌斑指数(PLI)、出血指数(BI)、探诊深度(PD)值比较,差异未见统计学意义(P>0.05);治疗后,观察组CAL、PLI、BI、PD值少于对照组(P<0.05).结论替硝唑溶液配和盐酸米诺环素可改善患者牙周指标,增强抗菌效果,有效缓解患者自觉症状,推荐临床应用.

Objective To investigate the clinical effects of root canal therapy with different disinfectants in patients with periodontal pulpal disease. Methods A total of 120 patients with periodontal pulp combined disease who underwent root canal treatment in General Hospital of Xishan Coal and Electricity Group from June 2017 to June 2018 were randomly divided into observation group and control group, with 60 cases in each group. The observation group was given tinidazole solution combined with minocycline hydrochloride, and the control group was given sodium hypochlorite solution combined with calcium hydroxide and chlorhexidine. The effects of the two groups were compared, and the changes of periodontal parameters in the two groups before and after treatment were analyzed. Results After 12 weeks of treatment, the total effective rate of the observation group (98. 33%, 59/60) was higher than that of the control group ( 90. 00%, 54/60 ). Before treatment, the clinical adhesion level ( CAL ), plaque index ( PLI ), bleeding index ( BI ), and depth of probing ( PD ) of the two groups were not significant different (P>0. 05). After treatment, the CAL, PLI, BI, and PD values in the observation group were lower than those in the control group ( P < 0. 05 ). Conclusions The combination of tinidazole solution and minocycline hydrochloride can improve the periodontal index of patients, enhance the antibacterial effect, effectively alleviate the patient's symptoms, with can be recommend to clinical application.