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炎症性肠病与心血管病关联研究回顾与现状 被引量：1

Retrospect and Current Situation between Inflammatory Bowel Disease and Cardiovascular Disease
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摘要 炎症性肠病(inflammatory bowel disease,IBD)是一类肠道的慢性非特异性炎症性疾病,包括溃疡性结肠炎(ulcerative colitis,UC)和克罗恩病(Crohn's dis﹣ease,CD).目前 IBD的发病机制尚不清楚,普遍认为免疫、遗传、感染以及环境因素在 IBD 的发病过程中起着重要作用.炎症反应在动脉粥样硬化、血栓形成及IBD的发病机制中起着必不可少的作用.考虑到IBD是一种全身炎症状态,伴随有促炎因子水平的升高,理所当然地预料IBD患者进展性动脉粥样硬化、血栓性损伤的并发症增加[1].在一项IBD患者心血管病的回顾研究[2]中,发现IBD和静脉血栓栓塞之间的正性关联;但与冠状血管疾病相关联的证据相对稀少.本文回顾近年来国内外发表的关于IBD共患心血管病的相关文献,介绍了IBD共患心血管病的相关研究现状.
作者 陈翠连 王帆 贾钧 李国珍 Chen Cuilian;Wang Fan;Jia Jun
机构地区 武汉市武昌医院 武汉大学中南医院 华中科技大学同济医学院协和武汉市红十会医院消化内科
出处 《医学新知》 CAS 2019年第4期418-420,共3页 New Medicine
关键词 炎症性肠病 克罗恩病 溃疡性结肠炎 心血管病
分类号 R574.62 [医药卫生—消化系统]
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  • 1Cui HF,Jiang XL.Treatment of corticosteroid-resistant ulcerative colitis with oral low molecular weight heparin[J].World Journal of Gastroenterology,1999,5(5):448-450. 被引量：24
  • 2Siddharth Singh,Harkirat Singh,Edward V. Loftus,Darrell S. Pardi.Risk of Cerebrovascular Accidents and Ischemic Heart Disease in Patients With Inflammatory Bowel Disease: A Systematic Review and Meta-analysis[J].Clinical Gastroenterology and Hepatology.2014(3)
  • 3Mathurin Fumery,Cao Xiaocang,Luc Dauchet,Corinne Gower-Rousseau,Laurent Peyrin-Biroulet,Jean-Frédéric Colombel.Thromboembolic events and cardiovascular mortality in inflammatory bowel diseases: A meta-analysis of observational studies[J].Journal of Crohn’s and Colitis.2013
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  • 7Seth D.Crockett,Richard A.Hansen,TilStürmer,RobinSchectman,JaneDarter,Robert S.Sandler,Michael D.Kappelman.Statins are associated with reduced use of steroids in inflammatory bowel disease: A retrospective cohort study[J].Inflamm Bowel Dis.2012(6)
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医学新知
2019年 第4期

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