老年综合评估与干预对帕金森病患者非运动症状及生活质量改善的效果分析

目的探讨老年综合评估(CGA)与干预对帕金森患者非运动症状和生活质量改善的作用.方法选择2015年6月至2018年2月帕金森病患者120例,随机分为干预组和对照组,每组各60例,入院后两组即进行CGA评估,根据评估结果,干预组除常规药物治疗外,根据评估结果给予多学科干预方案,对照组仅予常规药物对症治疗.干预期限为6个月,6个月后行第2次评估.结果经过6个月干预后,干预组帕金森病的非运动症状,包括便秘、尿失禁、抑郁、睡眠障碍、认知功能明显改善,干预组便秘缓解总有效率明显优于对照组(P<0.05),干预组匹茨堡睡眠质量指数量表(PSQI)、抑郁自评量表(SDS)、国际尿失禁咨询委员会-尿失禁问卷简表(ICI-Q-SF)评分显著低于对照组,简易智力状态检查量表(MMSE)评分显著高于对照组(P<0.05);日常生活能力量表ADL评分较对照组显著升高(P<0.05).结论老年综合评估与干预对帕金森非运动症状的改善起到积极的作用,并有助于提高帕金森病患者的生活质量.

Objective To explore the effect of comprehensive geriatric assessment(CGA)and intervention on the improvement of non-motor symptoms and quality of life in patients of Parkinson's Disease. Methods 120 patients with Parkinson's Disease admitted to our hospital from June 2015 to February 2018 were randomly divided into intervention group and control group,60 people in each group. After CGA evaluation,the intervention group was given multidisciplinary intervention program according to the evaluation results except conventional drug treatment,while the control group was only given conventional drug treatment. Intervention for 6 months. Results After the intervention,the results of non-motor symptoms including constipation,urinary incontinence,depression,sleep disorder and cognitive function in the intervention group were significantly improved. The total effective rate of constipation relief in the intervention group was significantly better than that in the control group(83.33% vs 65%,P<0.05). The scores of ICI-Q-SF,SDS,and PSQI were significantly lower than those of the control group(P<0.05). The scores of MMSE was significantly higher than those of the control group(P<0.05). The scores of ADL were significantly higher than those of the control group(65.07±21.01 vs 57.17±21.41, P<0.05). Conclusion Comprehensive geriatric assessment and intervention play a positive role in improving the non-motor symptoms and the quality of life of patients with Parkinson's Disease.