兰州市居民糖尿病患病现状及影响因素分析

Present situation and influencing factors of diabetes mellitus in Lanzhou residents

目的了解兰州市居民糖尿病的患病现状以及影响糖尿病患病的相关因素。方法随机抽取兰州市1525名市民作为研究对象,调查年龄、吸烟史、家族史以及糖尿病患病史,测量身高、体重、血压、腰围和静息心率,测定血脂、糖化血红蛋白、空腹血糖以及餐后2小时血糖,根据糖化血红白含量、空腹血糖水平、餐后2小时血糖水平以及是否有糖尿病患病史,将研究对象分为糖尿病组、糖尿病前期组和糖代谢正常组,研究兰州市糖尿病的患病情况及影响兰州市居民糖尿病患病的危险因素。结果①兰州市居民糖尿病和糖尿病前期的患病率分别为9.44%和14.23%;②糖尿病相关危险因素有年龄(P<0.05)、糖尿病家族史(P<0.05)、体重(P<0.05)、高血压(P<0.05)、高脂血症(P<0.05);③糖尿病组与糖代谢正常组比较,年龄、体重指数、收缩压、舒张压、腰围、糖化血红蛋白、血浆总胆固醇、甘油三酯、低密度脂蛋白胆固醇显著升高,高密度脂蛋白胆固醇显著降低(P<0.05)。结论年龄、糖尿病家族史、体重、高血压、高脂血症是兰州市糖尿病的危险因素。

Objective To investigate the prevalence of diabetes mellitus among residents in Lanzhou and the related factors affecting diabetes mellitus. Methods 1 525 citizens in Lanzhou city were randomly selected as the research objects,the age,smoking history,family history and history of diabetes were investigated.Measurement included the height,weight,blood pressure,waist circumference,and static resting heart rate blood lipid,glycosylated hemoglobin,fasting glucose,and blood glucose 2 hours after meal were measured.According to the content of glycosylated hemoglobin(HbA 1c),fasting blood glucose level,blood glucose 2 hours after meal and whether there was a history of diabetes,the objects of study were divided into diabetes groups,pre-diabetes and diabetes glucose metabolism to normal group.The prevalence of diabetes of Lanzhou and its risk factors were studied. Results ①The prevalence of diabetes and pre-diabetes among Lanzhou residents were 9.44% and 14.23%,respectively.②Diabetes risk factors were age ( P < 0.05 ),family history of diabetes ( P < 0.05 ),weight ( P < 0.05 ),hypertension ( P < 0.05 ),hyperlipidemia ( P < 0.05 ).③Age,body mass index,systolic blood pressure,diastolic blood pressure,waist circumference,HbA 1c,plasma total cholesterol,triglycerides,and low-density lipoprotein cholesterol were significantly increased and high-density lipoprotein cholesterol significantly decreased in diabetic group compared with the normal glucose metabolism group( P < 0.05 ). Conclusion Age,family history of diabetes,weight,hypertension and hyperlipidemia were risk factors for diabetes in Lanzhou.