胸腔镜肺大泡切除术对肺大泡患者机体应激反应及术后并发症的影响

Effect of thoracoscopic pulmonary bullectomy on stress response and postoperative complications in patients with bullae of lung

目的:探讨胸腔镜肺大泡切除术对肺大泡患者机体应激反应及术后并发症的影响.方法:选取某院收治的106例肺大泡患者,按照随机双盲法将其分为2组,每组各53例.对照组行传统开胸手术治疗,观察组行胸腔镜肺大泡切除术治疗.观察2组患者手术相关指标、住院时间、应激反应指标及术后并发症.结果:观察组术中出血量、手术时间、术后引流管留置时间、术后VAS评分及住院时间均低于对照组,差异有统计学意义(P<0.05);术后2组患者皮质醇(Cor)、去甲肾上腺素(NE)、血管紧张素 Ⅱ(AngⅡ)指标均高于术前,且对照组增加更显著,差异有统计学意义(P<0.05);并发症发生率观察组低于对照组,差异有统计学意义(P<0.05).结论:胸腔镜肺大泡切除术对肺大泡患者机体创伤小,恢复快,利于降低术后应激反应及并发症风险,缓解术后疼痛,缩短住院治疗时间.

Objective:To observe the effect of thoracoscopic pulmonary bullectomy on stress response and postoperative complications in patients with bullae of lung.Methods:106 patients with bullae of lung were randomly divided into two groups,with 53 cases in each group.The control group underwent conventional thoracotomy,and the observation group was treated with thoracoscopic pulmonary bullectomy.The surgical indexes,hospital stays,stress response indexes and postoperative complications in the two groups were observed.Results:Compared with the control group,the intraoperative bleeding volume,operation time,postoperative drainage tube indwelling time,postoperative VAS score and hospital stays in the observation group were lower or shorter(P<0.05).After the surgery,Cor,NE and AngII in the two groups were higher than before the surgery,and the control group increased more significantly(P<0.05).Compared with the control group,the incidence of complications in the observation group was lower(P<0.05).Conclusion:Thoracoscopic pulmonary bullectomy for patients with bullae of lung,with small trauma,can decrease postoperative stress response,relieve postoperative pain,reduce complications and shorten hospital stays.