甲状腺髓样癌的放射治疗新进展

Current status of radiotherapy for medullary thyroid carcinoma

甲状腺髓样癌(MTC)是一种源自甲状腺滤泡旁C细胞的神经内分泌肿瘤。甲状腺髓样癌的初始治疗通常是手术。临床分期较晚的患者,尽管进行了积极的手术治疗,但局部复发风险仍很高。随着辐射技术的改进,足够的放疗剂量可以有效地照射到高危区域,同时最小化周围关键组织结构的受照剂量。因此放射治疗应该是局部晚期甲状腺髓样癌的治疗选择,以提高局部区域控制。

Medullary thyroid carcinoma(MTC) is a neuroendocrine tumor derived from paracancerous C-cells of the thyroid gland.The initial treatment for medullary thyroid carcinoma is usually surgery.Patients with advanced clinical stage,despite active surgical treatment,have a high risk of local recurrence.With the improvement of radiation technology,sufficient radiation dose can effectively irradiate high-risk areas and minimize the exposure dose of key tissue structures around.Therefore,radiation therapy should be the treatment of locally advanced medullary thyroid carcinoma to improve local regional control.