绵萆薢化学成分研究(Ⅱ)

Study on the chemical composition of Dioscorea septemloba Thunb.

采用现代分离技术对绵萆薢的化学成分进行了分离纯化,并用波谱技术鉴定其结构.结果从该植物提取物中分离得到8个化合物,分别为:对羟基苯乙酮(1)、4-(对羟基苯基)-2-丁酮(2)、肉桂酸(3)、对羟基苯乙醇(4)、苯酚(5)、1-β-D-呋喃核糖基-1H-1,2,4-三氮唑(6)、薯蓣皂苷元-3-O-[α-L-吡喃鼠李糖(1→2)]-[α-L-吡喃鼠李糖(1→4)]-β-D-吡喃葡萄糖(7)、薯蓣皂苷元-3-O-[α-L-吡喃鼠李糖(1→2)]-β-D-吡喃葡萄糖(8).其中化合物1~6为首次从该植物分离得到,且化合物1、4、5、6是首次从该属植物中分离得到.

The modern separation techniques were applied to sepearating and purifying the chemical constituents of Dioscorea septemloba Thunb.,and spectroscopic technique was used to elucidate its structure.8 compounds were obtained and identified as 4′-hydroxyacetophenone(1),1-(4-hydroxyphenyl)-1-butanone(2),trans-cinnamic acid(3),4-hydroxyphenethyl alcohol(4),phenol(5),1-(β-D-ribofuranosyl)-1H-1,2,4-triazone(6),diosgenin bis-(α-L-rhamnopyranosyl)-(1→2 and 1→4)-β-D-glucopyranoside(7),diosgenin-3-O-α-L-rhamnopyranosyl(1→2)-β-D-glucopyranoside(8).Compounds 1-6 were separated and obtained for the first time from this plant,moreover,compounds 2,4,5 and 6 were separated and obtained from this genus for the first time.