心理护理干预对帕罗西汀治疗产后抑郁症患者临床疗效的影响

Effect of psychological nursing intervention on the clinical efficacy of paroxetine in the treatment of postpartum depression

目的 研究心理护理干预措施应用在帕罗西汀对产后抑郁症患者治疗当中的效果。方法 66例产后抑郁症患者作为研究对象,按随机方法分为观察组与对照组,每组33例。两组患者均常规应用帕罗西汀进行治疗,对照组采用治疗相关常规护理,观察组在此基础上配合心理护理干预。比较两组患者临床治疗效果、满意度,以及治疗前后汉密尔顿抑郁量表评分。结果 观察组患者临床治疗总有效率90.91%(30/33)明显高于对照组的63.64%(21/33),差异具有统计学意义(P<0.05)。观察组患者满意度93.94%(31/33)明显高于对照组的69.70%(23/33),差异具有统计学意义(P<0.05)。治疗前,观察组患者汉密尔顿抑郁量表评分(28.62±11.02)分与对照组的(27.26±10.26)分比较,差异无统计学意义(P>0.05);治疗后6周,观察组患者汉密尔顿抑郁量表评分(5.89±1.25)分明显低于对照组的(14.05±2.22)分,差异具有统计学意义(P<0.05)。结论 对产后抑郁症患者在应用药物帕罗西汀进行治疗的同时配合心理护理干预,可有效帮助患者改善临床症状,提升治疗效果,缓解患者的抑郁情绪,值得推广应用。

Objective To study the effect of psychological nursing intervention on the clinical efficacy of paroxetine in the treatment of postpartum depression. Methods A total of 66 postpartum depression patients as study subjects were randomly divided into observation group and control group, with 33 cases in each group. Both groups were treated with paroxetine. The control group received treatment-related conventional nursing, and the observation group received psychological nursing on this basis. Comparison was made on clinical effect, degree of satisfaction, Hamilton depression scale score before and after treatment between the two groups. Results The observation group had obviously higher total effective rate of clinical treatment as 90.91%(30/33) than 63.64%(21/33) in the control group, and the difference was statistically significant (P<0.05). The observation group had obviously higher degree of satisfaction as 93.94%(31/33) than 69.70%(23/33) in the control group, and the difference was statistically significant (P<0.05). Before treatment, there was no statistically significant difference in Hamilton depression scale score in the observation group as (28.62±11.02) points and (27.26±10.26) points in the control group (P>0.05). After 6 weeks of treatment, the observation group had obviously lower Hamilton depression scale score as (5.89±1.25) points than (14.05±2.22) points in the control group, and the difference was statistically significant (P<0.05). Conclusion For patients with postpartum depression, the application of paroxetine combined with psychological nursing intervention can effectively help patients improve clinical symptoms and treatment effects, relieve patients’depression. It is worthy of promotion and application.