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依托咪酯复合丙泊酚在ESVD患者麻醉中的应用

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摘要 目的探讨依托咪酯复合丙泊酚在内镜食管胃底静脉曲张精准断流术(ESVD)中的应用价值。方法选取择期行ESVD的60例患者,按照随机数字表法分为丙泊酚组(P组)和依托咪酯复合丙泊酚组(EP组),各30例。记录麻醉前(T1)、插管后(T2)、进镜时(T3)、手术30min时(T4)、术毕(T5)、拔管时(T6)MAP、HR;记录术中血管活性药物、羟乙基淀粉使用情况、手术结束至拔管时间;记录体动或呛咳、肌阵挛、恶心呕吐等不良反应发生情况及手术前后的肝功能情况。结果与T1比较,两组患者T3~T4时MAP、HR均降低(P<0.05);与EP组比较,P组T2~T4MAP更低(P<0.05)。EP组血管活性药物使用剂量、补液量低于P组(P<0.05),两组苏醒时间和拔除气管导管时间无差异(P>0.05)。与P组相比,EP组体动或呛咳发生率降低(P<0.05)。两组手术前后肝功能无明显变化(P>0.05)。结论依托咪酯复合用于ESVD术麻醉时,与单纯丙泊酚麻醉相比,血流动力学更平稳,不良反应少,麻醉效果满意。
出处 《解放军预防医学杂志》 CAS 2019年第9期150-151,128,共2页 Journal of Preventive Medicine of Chinese People's Liberation Army
基金 安徽省2018年度重点研究与开发计划项目(No.1804h08020286)
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