盐酸氨溴索大剂量用药与纤维支气管镜灌洗法对肺炎患者的效果

Effect of ambroxol hydrochloride high-dose drug use and fiberoptic bronchoscopic lavage on patients with pneumonia

目的:探讨盐酸氨溴索大剂量用药与纤维支气管镜灌洗法对肺炎患者的治疗效果。方法:收治肺炎患者72例,随机分为两组各36例,对照组采用盐酸氨溴索+振动排痰仪治疗,观察组采用大剂量盐酸氨溴索+纤维支气管镜灌洗法治疗,比较两组治疗效果。结果:观察组治疗后急性生理学和慢性健康状况评分(APACHEⅡ评分)明显低于对照组,而且观察组动脉血气指标较治疗前明显好转,且显著优于对照组,差异有统计学意义(P<0.05)。结论:对肺炎患者应用盐酸氨溴索大剂量用药与纤维支气管镜灌洗法治疗可有效减轻病情,改善动脉血气指标,对于促进患者康复有积极影响。

Objective:To investigate the therapeutic effect of ambroxol hydrochloride high-dose medication and fiberoptic bronchoscopy on pneumonia patients.Methods:72 patients with pneumonia were selected,they were randomly divided into the two groups with 36 cases in each group.The control group was treated with ambroxol hydrochloride + vibrating sputum sputum.The observation group was treated with high-dose ambroxol hydrochloride+fiberoptic bronchoscopy,and the therapeutic effects of the two groups were compared.Results:The acute physiology and chronic health status scoring system(APACHE Ⅱ score)showed that the scores of the observation group were significantly lower than those of the control group,and the arterial blood gas index of the observation group was significantly better than that of the control group,the difference was statistically significant(P<0.05). Conclusion:The application of ambroxol hydrochloride and high-dose bronchoscopy in patients with pneumonia can effectively alleviate the disease and improve the arterial blood gas index,which has a positive impact on the rehabilitation of patients.