硫酸镁治疗急性结石性胆囊炎的疗效及对胃肠功能的影响

Effect of magnesium sulfate on serum bilirubin, C-reactive protein, neutrophils, leukocytes and gastrointestinal function in patients with acute calculous cholecystitis

目的探讨应用硫酸镁治疗急性结石性胆囊炎的疗效及对胃肠功能的影响。方法选取2017年5月~2018年1月收治的急性结石性胆囊炎患者62例,将其按照随机数字表法分为对照组和研究组各31例,予以对照组患者常规治疗,研究组实施硫酸镁结合常规治疗,观察并对比两组患者的胃肠功能、白细胞、中性粒细胞、C反应蛋白以及血清胆红素情况。结果研究组患者治疗后胃动素(MTL)水平高于对照组,血管活性相关肠肽(VIP)水平低于对照组(P<0.05);研究组患者治疗后白细胞、中性粒细胞、C反应蛋白以及血清胆红素水平明显低于对照组(P<0.05)。结论应用硫酸镁对急性结石性胆囊炎患者进行治疗的效果满意,改善胃肠功能。

Objective To investigate the effect of magnesium sulfate on the treatment of patients with acute calculous cholecystitis and its effects on gastrointestinal function,white blood cells,neutrophils,C-reactive protein and serum bilirubin. Methods Sixty-two patients with acute calculous cholecystitis admitted to the hospital from May 2017 to January 1818 were enrolled. According to the random number table method,31 patients were divided into the comparison group and 31 patients in the study group,and the patients in the comparison group were treated routinely. Patients in the study group were treated with magnesium sulfate in combination with conventional therapy. The gastrointestinal function,white blood cells,neutrophils,C-reactive protein and serum bilirubin were observed and compared between the two groups. Results The MTL level in the study group was higher than that in the comparison group,and the VIP level was lower than the comparison group( P <0.05). Leukocytes,neutrophils,C-reactive protein,and serum bilirubin levels were measured in the study group,and were significantly lower than the comparison group( P < 0.05). Conclusion The application of magnesium sulfate in the treatment of patients with acute calculous cholecystitis is better,can effectively control the patient's white blood cells,neutrophils,C-reactive protein and serum bilirubin,so that patients' gastrointestinal function is improved.