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冠心病持续性房颤患者血清CRP意义及与心功能的关系 被引量:2

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摘要 目的研究冠心病持续性房颤患者血清C反应蛋白(CRP)意义及与心功能的关系。方法选取2016年1月~2018年6月收治的冠心病持续性房颤患者(106例)作为观察组,选取同期于接受健康体检者(106例)为对照组,采取酶联免疫法对所有患者的血清CRP水平进行检测,根据NYHA心功能分级标准将观察组患者分为Ⅰ级、Ⅱ级、Ⅲ级、Ⅳ级4个亚组,对各组患者的血清CRP水平进行对比分析。结果观察组患者的血清CRP水平明显高于对照组,差异有统计学意义(P<0.05)。观察组心功能Ⅰ级组的患者和心功能Ⅱ级组的患者血清CRP水平对比,差异无统计学意义(P>0.05)。心功能Ⅲ级组患者血清CRP水平明显高于心功能Ⅱ级组,心功能Ⅳ级组患者血清CRP水平明显高于心功能Ⅲ级组,差异均有统计学意义(P<0.05)。结论血清CRP水平上升与冠心病持续性房颤存在密切关系,且患者血清CRP水平也由于心功能不全程度加重不断上升,表明患者自身的炎症反应参与房颤及心衰的发生及其发展过程。
出处 《中国处方药》 2019年第10期153-154,共2页 Journal of China Prescription Drug
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