微量白蛋白检验在诊断肾小球疾病的价值分析

Analysis of the Value of Microalbumin Test in the Diagnosis of Glomerular Diseases

目的分析在诊断肾小球疾病时微量白蛋白检验的价值。方法方便选取2017年8月-2018年9月在该院接受治疗的80例糖尿病肾病患者和同期进行健康检查的80名健康人分别作为实验组和对照组,对两组均进行微量白蛋白检验,分析检验结果的阳性率和实验组患者阳性率及病程之间存在的关系。结果实验组尿微量白蛋白的阳性率(51.25%)和含量(56.75±5.88)mg/L较对照组[分别为0.00%、(11.28±3.76)mg/L]更高,差异有统计学意义(P<0.05);实验组患者尿微量白蛋白阳性率和含量会由于病程的增加而提升,病程超过13年微量蛋白的阳性率为84.6%,尿微量蛋白含量为(78.95±6.14)mg/L;病程为6~12年尿微量蛋白的阳性率为53.3%,尿微量蛋白含量为(33.88±5.35)mg/L;病程低于6年尿微量蛋白的阳性率为25.0%,尿微量蛋白含量为(24.13±4.26)mg/L,组间尿微量蛋白的阳性率和含量之间进行对比,差异有统计学意义(P<0.05)。结论微量白蛋白检验在肾小球疾病诊断、发展和判断患者预后当中价值比较高,应该在临床中进行推广。

Objective To analyze the value of microalbumin test in the diagnosis of glomerular diseases. Methods From August 2017 to September 2018,80 cases of diabetic nephropathy treated in our hospital and 80 cases of health examination at the same time were convenient used as experimental group and control group respectively. The microalbumin test was performed on both groups, and the positive rate of the test results and the positive of the experimental group were analyzed. The relationship between the rate and the course of the disease. Results The positive rate (51.25%) and content (56.75±5.88)mg/L of urine microalbumin in the experimental group were higher than those in the control group[0.00%,(11.28±3.76)mg/L], respectively, and the difference was statistically significant(P<0.05);the positive rate and content of urinary albumin in the experimental group will increase due to the increase of the course of disease. The positive rate of microprotein in the course of more than 13 years was 84.6%, and the content of microalbuminuria was (78.95±6.14)mg/L. The disease rate was 6-12 years, the positive rate of microalbuminuria was 53.3%, the urine microprotein content was (33.88±5.35)mg/L;the positive rate of urine microprotein was less than 2 years, the urine microprotein content was 25.0%, and the urine microprotein content was(24.13±4.26)mg/L, the positive rate and content of urine microprotein between groups were compared, and the difference was statistically significant(P<0.05). Conclusion The microalbumin test is of high value in the diagnosis, development and prognosis of glomerular diseases, and should be promoted in the clinic.