赖氨葡锌治疗小儿腹泻的临床效果

Clinical study on lysine hydrochloride and zinc gluconate in the treatment of diarrhea in children

目的分析赖氨葡锌对小儿腹泻治疗的效果。方法选择2018年1月~2019年3月在我院接受治疗的60例小儿腹泻患儿,将其随机分为对照组和观察组,每组30例。对照组采用综合治疗,观察组在综合治疗基础上使用赖氨葡锌治疗,比较两组患儿的治疗效果和腹泻、发热及呕吐的持续时间。结果观察组和对照组患儿的治疗总有效率分别为96.7%和80.0%,差异有统计学意义(P<0.05)。观察组腹泻、发热及呕吐的持续时间分别为(3.25±0.51)d、(2.01±0.61)d、(1.84±0.52)d,对照组腹泻、发热及呕吐的持续时间分别为(5.02±0.81)d、(3.78±0.71)d、(3.52±0.64)d,差异有统计学意义(P<0.05)。结论在小儿腹泻治疗的过程中使用赖氨葡锌,能够提高患儿的治疗效果,且缩短患儿腹泻、呕吐及发热的持续时间,促进患儿的康复,值得临床推广使用。

Objective To analyze the effect of lysine hydrochloride and zinc gluconate on the treatment of diarrhea in children.Methods 60 children with diarrhea in our hospital from January 2018 to March 2019 were randomly divided into control group and observation group,with 30 cases in each group.The control group was given comprehensive treatment.The observation group was treated with lysine hydrochloride and zinc gluconate on the basis of comprehensive treatment.The treatment effect and the duration of diarrhea,fever and vomiting of the two groups were compared.Results The total effective treatment rates of the children in the observation group and the control group were 96.7%and 80.0%,respectively,and the difference was statistically significant(P<0.05).The duration of diarrhea,fever and vomiting in the observation group were(3.25±0.51)d,(2.01±0.61)d,(1.84±0.52)d,and the duration of diarrhea,fever and vomiting in the control group were(5.02±0.81)d,(3.78±0.71)d,(3.52±0.64)d,and the difference was statistically significant(P<0.05).Conclusion The use of lysine hydrochloride and zinc gluconate in the treatment of diarrhea in children can improve the therapeutic effect of children,shorten the duration of diarrhea,vomiting and fever,and promote the rehabilitation of children.It is worthy of clinical promotion.