期刊文献+

县域医院乳腺癌患者生存质量影响因素的调查分析 被引量:1

Investigation and analysis of influencing factors on quality of life of breast cancer patients in county hospitals
下载PDF
导出
摘要 目的调查分析县域医院乳腺癌患者的生存质量影响因素。方法回顾性分析我院收治的315例乳腺癌患者的临床资料,分析影响患者生存率的因素。结果随访期间,0期乳腺癌患者的生存率为100.00%;Ⅰ、Ⅱ期乳腺癌患者的生存率显著高于Ⅲ、Ⅳ期(P<0.05)。Lminal A型和Lminal B型乳腺癌患者的生存率显著高于三阴性型(P<0.05)。使用曲妥珠单抗治疗的HER-2阳性乳腺癌可减少术后转移。结论虽然县域医院在乳腺癌的诊疗方面仍存在较大的提升空间,但随着医疗技术水平的进步、抗肿瘤药物的可及性改善及国内外乳腺癌指南的推广,县域医院乳腺癌的诊疗和预后将会日趋完善。 Objective To investigate and analyze the influencing factors on quality of life of breast cancer patients in county hospitals. Methods The clinical data of 315 breast cancer patients admitted to our hospital were retrospectively analyzed, and influencing factor of the survival rate was analyzed. Results During follow-up, the survival rate of stage 0 breast cancer patients was 100.00%. The survival rate of breast cancer patients with stageⅠ,Ⅱ were significantly higher than those of stage Ⅲ,Ⅳ(P<0.05). The survival rate of patients with Lminal A and Lminal B breast cancer were higher than those of triple negative breast cancer(P<0.05). The using of trastuzumab in treatment of HER-2 positive breast cancer can reduce metastasis after operation. Conclusion Although the diagnosis and treatment of breast cancer in county hospitals still has a large space for improvement, the progress of medical technology, the improvement of the accessibility of anti-tumor drugs and the promotion of domestic and foreign guidelines for breast cancer, the diagnosis, treatment and the prognosis of breast cancer in county hospitals will be gradually improved.
作者 任船 周红娟 葛荣忠 REN Chuan;ZHOU Hong-juan;GE Rong-zhong(Shuyang Hospital Affiliated of Xuzhou Medical University, Suqian 223600, China)
出处 《临床医学研究与实践》 2019年第28期34-35,共2页 Clinical Research and Practice
关键词 县域医院 乳腺癌 保乳术 生存率 county hospital breast cancer breast conserving surgery survival rate
  • 相关文献

参考文献4

二级参考文献38

  • 1张瑰红,施达仁,梁晓曼,侯景辉,康苏娅,朱卫东,李晓兵,邵云,陈丽荣,周燕.显色原位杂交和免疫组织化学检测乳腺癌HER2/neu基因状况和蛋白表达的对照性研究[J].中华病理学杂志,2006,35(10):580-583. 被引量:29
  • 2<乳腺癌HER2检测指南>编写组,霍临明.乳腺癌HER2检测指南[J].中华病理学杂志,2006,35(10):631-633. 被引量:164
  • 3Heller W, Mazhar D, Ward R, et al. Neoadjuvant 5-fluorouraeil, epirubicin and cyclophosphamide chemotherapy followed by docetaxel in refractory patients with locally advanced breast cancer [J]. OncolRep, 2007, 17(1): 253-259.
  • 4Gonzalez-Angulo AM, blorales-Vasquez F, Hortobagyi GN. Overview of resistance to systemic therapy in patients with breast cancer[ J]. Adv Exp Med Biol, 2007, 608:1 -22.
  • 5van Dongen JA, Voogd AC, Fentiman IS, et al. Long-term results of a randomized trial comparing breast-conserving therapy with mastectomy: European Organization for Research and Treatment of Cancer 10801 trial[ J]. Natl Cancer Inst, 2000, 92 (14) : 1143 - 1150.
  • 6Kokubo M, Mitsumori M, Ishikura S, et al. Results of breast-conserving therapy for early stage breast cancer: kyoto university experiences[J]. Am J Clln Oneol, 2000, 23(5) : 499 -505.
  • 7Foulkes WD, Chappuis PO, Wong N, et al. Primary node negative breast cancer in BRCA1 mutation carriers has a poor outcome [ J]. Ann Oncol, 2000, 11(3) : 307 -313.
  • 8Thomas JS, Julian HS, Green RV, et al. Histopathology of breast carcinoma following neoadjuvant systemic therapy: a common association between letrozole therapy and central scarring [J].Histopathology, 2007, 51(2) : 219 -226.
  • 9Veronesi U, Caseinelli N, Mariani L, et al. Twenty-year follow-up of a randomized study comparing breast-conserving surgery with radical masteetomy for early breast cancer[J].N Engl J Med, 2002, 347(16) : 1227 -1232.
  • 10Fisher B, Jeong JH, Anderson S, et al. Twenty-five-year follow-up of a randomized trial comparing radical masteetomy, total mastectomy, and total mastectomy followed by irradiation [ J ]. N Engl J Med, 2002, 347(8) : 567 -575.

共引文献409

同被引文献13

引证文献1

二级引证文献30

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部