高含量阿维菌素微囊悬浮剂的制备

Development of High-loading Abamectin CS Formulation

为开发高含量的阿维菌素微囊悬浮剂配方,提高阿维菌素紫外光降解稳定性,采用界面聚合的方法,以聚合MDI和乙二胺为囊皮材料单体,筛选出高溶解能力的新型溶剂POWERBLOXTMSV-17及配套的乳化剂、分散剂,开发了3%~5%阿维菌素微囊悬浮剂配方。该配方包覆率大于95%,热贮稳定性、冷贮稳定性及稀释稳定性均合格。与乳油产品相比,包覆后的有效成分在紫外光照下的降解率明显降低。

To explore high-loading abamectin CS formulation and improve active ingredient stability under UV irritation, interfacial polymerization method was used to develop CS formulation by using reactive monomers comprising isocyanate and amine groups. New high solvency solvent was developed to enable high abamectin concentration. Matched emulsifiers and dispersants were screened out. Experimental results indicated that the encapsulation rate of abamectin CS formulation was more than 95%. And prepared formulations showed qualified storage stability and dilution stability. Compared to EC formulation, abamectin active ingredient in CS formulation had much lower degradation rate.