肝硬化门静脉高压的介入治疗进展

Research advances in interventional treatment of cirrhotic portal hypertension

门静脉高压是肝硬化失代偿期的主要临床表现之一。肝硬化门静脉高压导致的诸如食管胃底静脉曲张出血、脾功能亢进、难治性腹水等一系列并发症严重威胁人类健康。自20世纪70年代放射介入技术开始应用于门静脉高压症的治疗以来,通过近几十年的发展,其技术不断成熟,更多的改良及新技术被应用于临床,其有效性和安全性也得到越来越多的认证。归纳了近年来国内外的相关文献,对介入技术在肝硬化门静脉高压患者中的临床应用进展作一综述,以指导肝硬化门静脉高压患者的治疗。

Portal hypertension is one of the main clinical manifestations of decompensated cirrhosis.A series of complications due to cirrhotic portal hypertension,such as esophagogastric variceal bleeding,hypersplenism,and intractable ascites,greatly threaten human health.Since the application of the radiological interventional technique in the treatment of portal hypertension in the 1970s,this technique has gradually become mature over the past few decades,and more improvements and new techniques have been applied in clinical practice,with an increasing number of evidence for its efficacy and safety.This article summarizes related articles in China and foreign countries and reviews the clinical application of interventional techniques in patients with cirrhotic portal hypertension,in order to guide the treatment of patients with cirrhotic portal hypertension.