血小板与早产儿支气管肺发育不良关系的研究进展

Progress on the correlation between platelet and bronchopulmonary dysplasia in premature infants

支气管肺发育不良(BPD)常见于早产儿,其病死率及预后不容乐观,成为早产儿最棘手的问题之一。近年来,随着对BPD研究的不断深入,以肺泡发育阻滞及肺微循环障碍为病理特征的新型BPD日益得到重视,尤其肺部血管发育在BPD形成过程中的作用得到更多的关注。血小板是血管形成及发育过程中不可或缺的成分,因此,其可能参与了BPD的发病。本文就血小板在BPD发病过程中可能的作用及研究进展进行综述。

Bronchopulmonary dysplasia(BPD) is common in premature infants.Because of its high mortality and bad prognosis,BPD has been a big problem for premature infants.With the intensive development of BPD researches recently,the new type of BPD mainly characterized by alveolar growth retardation and pulmonary microcirculation disorder is getting increasing attention,especially the role of pulmonary microcirculation disorder in the development of BPD.Platelet is an indispensable part of the formation and development of blood vessels,so it may be involved in the pathogenesis of BPD.This paper reviews research progresses and the possible effect of platelet on the pathogenesis of BPD.