摘要
目的分析重性抑郁障碍患者认知功能对自杀意念的影响。方法选取2017年1月至2018年9月在北京回龙观医院的住院重性抑郁障碍患者108例,根据自杀意念自评量表(self-rating idea of suicide scale,SIOSS)评分,分为有自杀意念组(n=48)和无自杀意念组(n=60)。采用自制一般情况调查表收集被试一般资料,采用重复成套神经心理状态测量(repeatable battery for the assessment of neuropsychological status,RBANS)评定认知功能。采用Logistic回归对各相关因素进行分析。结果(1)经评定有自杀意念者为48例,重性抑郁障碍患者自杀意念发生率44.4%。(2)有自杀意念组[RBANS总分(63.0±7.9)分;RBANS即刻记忆(62.7±8.8)分;RBANS视觉广度(67.2±10.0)分;RBANS言语功能(83.3±13.8)分;RBANS注意(85.3±11.9)分;RBANS延时记忆(53.5±7.7)分]和无自杀意念组[RBANS总分(73.8±7.7)分;RBANS即刻记忆(70.8±7.6)分;RBANS视觉广度(72.7±9.8)分;RBANS言语功能(91.5±4.5)分;RBANS注意(99.9±8.5)分;RBANS延时记忆(62.3±9.7)分]RBANS总分及各因子分的差异均有统计学意义(F=6.335~46.660,P<0.05),有自杀意念组均比无自杀意念组评分低。(3)Logistic回归结果显示,受教育年限是自杀意念的危险因素(β=0.289,P=0.013,OR=1.335,95%CI=1.063~1.676),RBANS注意因子(β=-0.161,P=0.000,OR=0.851,95%CI=0.778~0.931)、RBANS延时记忆因子(β=-0.151,P=0.006,OR=0.860,95%CI=0.772~0.957)是自杀意念的保护因素。结论认知功能对抑郁患者的自杀意念有影响,注意和延时记忆是自杀意念的保护因素。
Objective To analyze the influence of cognition on suicidal ideation in patients with major depressive disorder. Methods A total of 108 inpatients with major depressive disorder from January 2017 to September 2018 in Beijing Huilongguan Hospital were enrolled.They were divided into suicidal ideation group (n=42) and non-suicidal ideation group (n=66) by the self-rating idea of suicide scale (SIOSS). Cognition was assessed by Repeatable Battery for the Assessment of Neuropsychological Status(RBANS). The general situation was assessed by self-made general situation questionnaire.The related factors were analyzed by Logistic regression. Results (1) The rate of suicidal ideation was 44.4% in patients with major depressive disorder.(2) The total score of RBANS and five-factor scores of RBANS in suicidal ideation group were lower than those in non-suicidal ideation group(total RBANS score(63.0±7.9) vs (73.8±7.7);immediate memory:(62.7±8.8) vs (70.8±7.6);visual span:(67.2±10.0) vs (72.7±9.8);speech function:(83.3±13.8) vs (91.5±4.5);attention:(85.3±11.9) vs (99.9±8.5);delayed memory:(53.5±7.7) vs (62.3±9.7), F=6.335-46.660, P<0.05).(3)Logistic regression showed, years of education were risk factors for suicidal ideation(β=0.289, P=0.013, OR=1.335, 95%CI=1.063-1.676), RBANS attention factor(β=-0.161, P=0.000, OR=0.851, 95%CI=0.778-0.931)and RBANS delayed memory factor score(β=-0.151, P=0.006, OR=0.860, 95%CI=0.772-0.957)were protective factors for suicidal ideation. Conclusion Cognitive function has an impact on suicide ideation of depressive patients, mainly attention and delayed memory are protective factors for suicide ideation.
作者
李伟
冀成君
杨甫德
卞清涛
童永胜
王志仁
杨可冰
蔡海鹏
王鑫
谭云龙
Li Wei;Ji Chengjun;Yang Fude;Bian Qingtao;Tong Yongsheng;Wang Zhiren;Yang Kebing;Cai Haipeng;Wang Xin;Tan Yunlong(Physical Therapy Center, Peking University Huilongguan Clinical Medical School, Beijing Huilongguan Hospital, Beijing 100096, China;Hospital Office Department, Peking University Huilongguan Clinical Medical School, Beijing Huilongguan Hospital, Beijing 100096, China;The First Clinical Department, Peking University Huilongguan Clinical Medical School, Beijing Huilongguan Hospital, Beijing 100096, China;Center for Psychological Crisis Research and Intervention, Peking University Huilongguan Clinical Medical School, Beijing Huilongguan Hospital, Beijing 100096, China;Science and Technology Department, Peking University Huilongguan Clinical Medical School, Beijing Huilongguan Hospital, Beijing 100096, China)
出处
《中华行为医学与脑科学杂志》
CAS
CSCD
北大核心
2019年第9期827-831,共5页
Chinese Journal of Behavioral Medicine and Brain Science
基金
北京市科学技术委员会"首都临床特色应用研究"专项资助课题(Z161100000516047)
北京市医院管理局临床医学发展专项经费资助(XMLX201834).
关键词
抑郁障碍
自杀意念
认知
注意障碍
记忆
Depression
Suicidal ideation
Cognition
Attention
Memory