急性缺血性卒中血管内治疗筛选病例的研究进展

Recent advance in selecting patients about endovascular treatment of acute ischemic stroke

急性缺血性卒中发病率呈逐年上升趋势,并且具有很高的致残率和致死率.由于静脉阿替普酶溶栓治疗急性缺血性卒中的局限性,2015年以来5大临床前瞻随机双盲多中心临床研究证实新一代血管再通策略(主要是可回收支架)在大血管闭塞导致的急性缺血性卒中明显优于单独内科治疗,各国脑卒中指南也相应进行更新.本文围绕5大临床研究及欧洲、美国最新指南中关于筛选合适卒中患者进行机械取栓的研究进展综述如下.

The incidence of acute ischemic stroke rises year by year, and has a high disability rate and mortality rate. Due to limitations of intravenous alteplase in the treatment of acute ischemic stroke, five randomized trials have demonstrated the benefit of new-generation endovascular recanalization therapies(primarily stent retrievers) over medical therapy alone among patients with acute ischemic stroke since 2015, and the guidelines with acute ischemic stroke guidelines have updated in many countries. This review focuses on five major clinical studies and the latest guidelines in Europe and the United States on the selection of suitable stroke patients for mechanical thrombectomy. The following is a review of the research progress.