温胆汤预防性应用对老年ICU患者谵妄风险的影响

Effect of Preventive Application of Wendan Decoction on Delirium Risk in Elderly ICU Patients

[目的]研究温胆汤预防性应用对老年ICU患者谵妄风险影响。[方法]选取医院重症医学科2017年1月-2019年1月收治的78例ICU患者,以随机数表法分为观察组与对照组各39例。对照组给予常规治疗以预防谵妄,即积极治疗原发病,心理护理等。观察组在常规治疗的同时加用温胆汤预防ICU患者出现谵妄。对比两组用药后谵妄发生率及ICU住院时间,另外统计观察组患者用药后不良反应发生率。[结果]观察组用药后谵妄发生率7.69%显著低于对照组25.64%,且观察组ICU住院时间显著短于对照组,差异有统计学意义(P<0.05);观察组用药后不良反应总发生率28.21%,但均为轻微反应,未经特殊处理,继续治疗后症状消失。[结论]温胆汤用于老年ICU患者可降低谵妄的发生风险、缩短ICU住院时间,且用药安全,值得临床推广。

[Objective]To study the effect of preventive application of Wendan decoction on delirium risk in elderly ICU patients.[Methods]Seventy-eight ICU inpatients admitted to our hospital from January 2017 to January 2019 were enrolled in the study.They were randomly divided into observation group and control group,39 cases each.Patients in the control group were given routine treatment to prevent delirium,that is,active treatment of primary diseases,psychological nursing,etc.In the observation group,Wendan decoction was added to prevent delirium in ICU patients at the same time of routine treatment.The incidence of delirium and length of stay in ICU were compared between the two groups,and the incidence of adverse reactions was also counted in the observation group.[Results]The incidence of delirium in the observation group was 7.69%significantly lower than that in the control group(25.64%),and the hospitalization time of ICU in the observation group was significantly shorter than that in the control group(P<0.05).The total incidence of adverse reactions in the observation group was 28.21%,but all of them were mild.Without special treatment,the symptoms disappeared after continued treatment.[Conclusion]Wendan decoction can reduce the risk of delirium in elderly ICU patients,shorten the length of ICU hospitalization,and is safe to use,which is worthy of clinical promotion.