无创正压通气法辅助治疗呼吸衰竭合并重症支气管哮喘的效果

Effect of non-invasive positive pressure ventilation in the auxiliary treatment of respiratory failure complicated with severe bronchial asthma

目的探析无创正压通气法辅助治疗呼吸衰竭合并重症支气管哮喘的临床效果,为临床深入研究提供参考。方法将我院呼吸内科2017年1月至2018年10月收治的88例呼吸衰竭合并重症支气管哮喘患者作为研究对象,将患者按治疗方法不同分为研究组与参照组,各44例。参照组给予常规治疗,研究组在常规治疗的基础上给予无创正压通气法辅助治疗。比较两组患者的临床疗效、并发症发生情况及治疗前、后的肺功能指标。结果研究组患者的治疗总有效率为90.91%,显著高于参照组的75.00%,差异具有统计学意义(P<0.05);治疗后,研究组患者的并发症总发生率为6.82%,低于参照组的25.00%,差异具有统计学意义(P<0.05);治疗前,两组患者的FEV1、FVC、FEV1/FVC比较,差异无统计学意义(P>0.05),治疗后,两组患者的FEV1、FVC、FEV1/FVC均升高,且研究组高于参照组,差异具有统计学意义(P<0.05)。结论无创正压通气法在呼吸衰竭合并重症支气管哮喘患者的辅助治疗中具有确切的效果,能够缓解各项临床症状,改善肺功能通气情况,降低患者并发症发生率,促进患者早日康复,对临床深入治疗具有重要的参考价值。

Objective To explore the clinical effect of non-invasive positive pressure ventilation in the auxiliary treatment of respiratory failure complicated with severe bronchial asthma, and to provide reference for further clinical research. Methods Eighty-eight patients with respiratory failure and severe bronchial asthma in the respiratory medicine department of our hospital from January 2017 to October 2018 were selected as the study subjects. The patients were divided into study group and reference group according to different treatment methods, with 44 cases in each group. The reference group was given routine treatment, while the study group was given non-invasive positive pressure ventilation on the basis of the routine treatment. The clinical efficacy, complications and pulmonary function indexes before and after treatment in the two groups were compared. Results The total effective rate of treatment in the study group was 90.91%, which was higher than 75.00% in the reference group, and the difference was statistically significant (P<0.05). After treatment, the total incidence of complications in the study group was 6.82%, which was lower than 25.00% in the reference group, and the difference was statistically significant (P<0.05). Before treatment, there were no significant differences in FEV1, FVC and FEV1/FVC between the two groups (P>0.05);after treatment, the levels of FEV1, FVC and FEV1/FVC in the two groups increased, and those in the study group were higher than the reference group, the differences were statistically significant(P<0.05). Conclusion The non-invasive positive pressure ventilation in the auxiliary treatment of respiratory failure complicated with severe bronchial asthma has an exact clinical effect, and it can relieve various clinical symptoms, improve lung function ventilation, reduce the incidence of complications and promote early recovery of patients. It has important reference value to clinical deep treatment.