CLAG方案治疗ETO阴性合并CEBPA突变WT1阳性急性髓系白血病M2一例并文献复习

Acute myeloid leukemia M2 patient with negative ETO combined with CEBPA mutation and positive WT1 treated by CLAG regimen: report of one case and review of literature

目的观察CLAG方案治疗ETO阴性合并CEBPA突变WT1阳性急性髓系白血病(AML)M2的临床疗效。方法对兰州军区兰州总医院1例采用CLAG方案治疗的ETO阴性合并CEBPA突变WT1阳性AML-M2患者的诊疗情况进行分析,并复习相关文献。结果该例患者行IA方案化疗1个疗程后未获得缓解,改行CLAG方案化疗1个疗程,复查骨髓完全缓解,后转外院进一步治疗。结论CLAG方案治疗ETO阴性合并CEBPA突变WT1阳性AML-M2患者短期疗效良好,长期疗效仍需积累更多的病例进一步观察。