摘要
针对3D打印和喷丝成型两种不同微加工方法制备的人造血管壁面特征对其内部液态流场的影响开展仿真研究。借助商用Comsol软件,研究了不同壁面拓扑形貌,结构尺寸和流体粘度等因素对人造血管内部流场的影响规律分析。结果表明:3D打印制备的人造血管内壁面凸起阵列结构在流场内形成了液体滞留区,该区域面积不随液体粘度的变化而变化,而会随着凸起结构尺寸的变大而变大;当滞留区带有血栓时,滞留区域面积进一步增大,容易引起血小板富集,因此,3D打印的人造血管壁面凸起结构对于血栓具有诱发和强化的作用。
Effects of artificial vessel wall structure prepared by 3 D print and spinning on the liquid flow field is simulated.Based on the fluid simulation module of the commercial Comsol software,the influence of the structure size and fluid viscosity on the internal flow field of artificial vessel are analyzed.The results show that stagnation zones are formed in the flow field of artificial vessel prepared with 3 D print,and increase with the increase of the projection size,but did not vary with the liquid viscosity.Through simulating the stagnation zones with thrombus block,it is proved that projection array has the enhancement effect on the thrombus block formulation inside of the artificial vessel wall.
作者
王桂莲
孙云娜
姚锦元
王艳
丁桂甫
章巧琪
WANG Guilian;SUN Yunna;YAO Jinyuan;WANG Yan;DING Guifu;ZHANG Qiaoqi(Sctool of Electronie and Electrical Engiceering,Shanghac University of Engineering Sciecce,Shanghai 201620,China;National Key Laboratory of Science and Technology on Micro/Nano Fabrication,Sctool of Electronic Information and Electrical Engineering,Shanghai Jiao Tong University,Shanghai 200240,China;Shanghai Baoshan Hospital of Integrated Traditional Chinese and Western Medicine,Shanghai 210999,China)
出处
《传感器与微系统》
CSCD
2019年第10期4-7,共4页
Transducer and Microsystem Technologies
基金
上海市科委项目(12JC1404902)
关键词
人造血管
微加工
3D打印
流场仿真
artificial vessel
micro-fabrication
3D print
flow field simulation
