腹腔镜与传统睾丸下降固定术对隐睾患儿的肝功能以及机体炎症反应的影响

Effects of laparoscopy and traditional testicular descent fixation on liver function and inflammatory response of children with cryptorchidism

目的探讨腹腔镜与传统睾丸下降固定术对隐睾患儿的肝功能以及机体炎症反应的影响。方法选取扬州大学附属医院小儿外科诊治的80例隐睾患儿作为研究对象。将其随机分成观察组和对照组,每组40例。观察组患儿予以腹腔镜下睾丸下降固定术,对照组患儿予以传统睾丸下降固定术,比较两组患儿的肝功能和机体炎症水平变化情况。结果观察组患儿术后2h的血清TBIL、ALB、PTA水平均较术前降低(均P<0.05),术后24h逐渐恢复正常;观察组患儿术后的血清CRP、TNF-α、IL-6水平均低于对照组患儿(均P<0.05)。结论腹腔镜下睾丸下降固定术与传统睾丸下降固定术比较,手术创伤小,可以降低患儿机体的炎症反应水平。腹腔镜下睾丸下降固定术术后患儿会出现暂时性的肝功能波动,但24h后会逐渐恢复至正常。

Objective To explore the effects of laparoscopy and traditional testicular descent fixation on liver function and inflammatory response of children with cryptorchidism. Methods 80 children with cryptorchidism treated in department of pediatric surgery of Affiliated Hospital of Yangzhou University were randomly divided into control group(40 cases) and observation group(40 cases). They were treated with traditional testicular descent fixation and laparoscopic testicular descent fixation respectively. The changes of liver function and body inflammation level were compared between the two groups. Results The levels of serum TBIL, ALB and PTA of the observation group significantly decreased 2 hours after the operation(all P<0.05), and gradually returned to normal 24 hours after the operation. The levels of serum CRP、TNF-α、IL-6 of the observation group were significantly lower than those of the control group(all P<0.05). Conclusions Compared with traditional testicular descent fixation, laparoscopic testicular descent fixation causes less trauma and can reduce the level of inflammation in children patients. After laparoscopic testicular descent fixation, temporary fluctuation of liver function may occur, but it will gradually return to normal after 24 hours.