青春期功能失调性子宫出血诊治进展

Progress in the diagnosis and treatment of hebetic dysfunctional uterine bleeding

青春期功能失调性子宫出血(hebetic dysfunctional uterine bleeding,以下简称青春期功血)多为无排卵性功血,是指初潮后1年~2年内由于下丘脑-垂体-卵巢轴(hypothalamic-pituitary-ovarian axis,HPO)发育不完善,引起生殖内分泌系统紊乱而造成的子宫长期无规律性出血,为青春期女性(10岁~19岁)常见疾病。治疗方法包括药物和手术,目前临床多以复方口服避孕药、雌孕激素序贯疗法、雌激素、孕激素等激素类药物治疗为主。本文对近年来青春期功血的相关诊治进展加以综述。

Hebetic dysfunctional uterine bleeding is a non-ovulatory dysfunctional uterine bleeding. It refers to the long-term irregular bleeding of uterus caused by the disorder of the reproductive endocrine system within 1 to 2 years after menarche due to the imperfect development of the hypothalamic-pituitary-ovarian axis. It is a common disease among adolescent girls from 10 to 19 years old. Therapeutic methods to this disease include drugs and surgery. At present, the clinical treatments are mainly hormone drugs, such as combined oral contraceptives, sequential therapy with estrogen and progesterone, estrogen and progesterone. This article will review the progress in the diagnosis and treatment of hebetic dysfunctional uterine bleeding in recent years.