不同类型生物补片在开放式无张力疝修补术中的回顾性对照研究

Different types of biological mesh in open tension-free hernia repair:A retrospective controlled study

目的观察猪小肠黏膜下层脱细胞基质补片与牛心包补片用于开放式无张力疝修补术中治疗腹股沟疝情况,探讨不同类型生物补片治疗腹股沟疝的临床效果及两种类型生物补片的对照研究分析。方法回顾性分析2016年5月至2018年1月,上海市松江区方塔中医医院运用两种类型生物补片行开放式无张力疝修补术治疗腹股沟疝的86例患者临床资料,按照不同类型生物补片分为2组。观察2组患者的手术指标、住院指标及随访期并发症发生情况。比较不同类型生物补片在应用于治疗腹股沟疝的手术安全性和短期疗效。结果接受非交联SIS补片和交联牛心包补片的患者在手术时间、住院天数和术后VAS疼痛评分方面比较,差异均无统计学意义(Z=-1.27、-0.05、-0.63,P均>0.05)。2组在术后1周、1个月及3个月血清肿的发生情况比较,差异均无统计学意义(χ^2=0.31、0.39、1.16,P>均0.05)。2组患者术后均无发生阴囊血肿、慢性疼痛、异物感、复发、感染及肠道相关并发症。结论猪小肠黏膜下层脱细胞基质补片与牛心包补片均用于开放式无张力疝修补术中治疗腹股沟疝的临床效果是安全、可行的。

Objective To observe the effect of porcine small intestine submucosa mesh versus bovine pericardium mesh on the treatment of inguinal hernia with open tension-free hernia repair. To investigate the clinical value of different types of biological mesh on the treatment of inguinal hernia and to analyze the two types of biological meshes. Methods The data of 86 patients with inguinal hernia treated with two types of biological meshes undergoing open tension-free hernia repair from May 2016 to January 2018 in Fangta hospital of Traditional Chinese Medicine were retrospectively analyzed. These patients were divided into two groups according to different types of biological meshes. The surgical indexes, hospitalization indexes and complications of the two groups were observed. The safety and short-term efficacy of different types of biological meshes in the treatment of inguinal hernia were compared. Results Of the 86 patients, 46 patients underwent porcine small intestine submucosa mesh and 40 patients underwent bovine pericardium mesh. No statistical difference was observed in operation time, hospital stay, postoperative pain score, postoperative complications between two groups (all P>0.05). No foreign body sensation, recurrence, chronic pain, and intestinal related complications were found in all patients. Conclusion Both porcine small intestine submucosa mesh and bovine pericardium mesh are safe and feasible for the treatment of inguinal hernia in open tension-free hernia repair.