门静脉血栓与肝移植

Portal vein thrombosis and liver transplantation

门静脉血栓形成(PVT)是指门静脉主干以及门静脉属支内血栓形成。由于PVT常缺乏特征性表现,主要依赖于术前影像学检查发现,甚至在术中偶然发现PVT。随着我国肝移植事业的不断发展,移植过程中发现PVT的案例越来越多,PVT已不再是肝移植禁忌证。因此,针对PVT的诊断、治疗以及移植过程中的处理方法显得尤为重要。本文根据国内外最新研究进展及经典文献报道,对肝移植中PVT展开综述。

Portal vein thrombosis (PVT) is defined as thrombosis in main portal vein and its tributary. Because of lacking specific clinical characteristics, most PVT was detected through imageological examination before transplantation, or discovered by accident during surgery. With rapid development of liver transplantation in China, more liver transplantation recipients with PVT were found during transplantation, and PVT is no longer the contraindication of liver transplantation. Therefore, reasonable diagnosis and treatment, and effective management during transplantation aiming at PVT is important. This review will elucidate the recent domestic and international progress in the aspect of PVT in liver transplantation.